Joe Awards, news

Joe awarded Frontiers for the Future project funding of €791k

Joe has been awarded a Frontiers for the Future Project award worth €791,010 to support new research into functional materials to prevent bacterial infection. Leveraging bioinorganic and carbohydrate chemistry concepts into a new approach. This funding will allow the Byrne Research Group to expand and explore new areas of research. Recruitment for new PhD students is already underway, along with additional advanced equipment to facilitate the research. More details are in the press release from UCD Chemistry below.

Joe spoke about the project and the funding at the end of KFM’s Kildare Today programme on 21/05/202: on-air interview (0:31:50-end, [audio clip]).

The UCD School of Chemistry has achieved a major double-win in the latest Research Ireland Frontiers for the Future funding round. Dr. Charles Loh (Awards Stream) and Dr. Joseph Byrne (Projects Stream) have been awarded a combined €2.7 million to lead two visionary projects: LIGHT4CARB and GlycoMetalGuard.

This funding milestone cements UCD’s standing as a premier European hub for fundamental chemistry, bridging the gap between curiosity-driven science and global challenges in sustainability and human health. Furthermore, this achievement is a significant testament to UCD’s leading reputation at the global forefront of innovative carbohydrate chemistry.

The Frontiers for the Future Programme—a flagship initiative of the newly established Research Ireland—specifically targets ambitious, “high-risk, high-reward” research. It is designed to empower Irish scientists to challenge existing boundaries of knowledge, delivering breakthroughs with the potential for profound societal and economic impact.

LIGHT4CARB: Led by Dr. Charles Loh, the LIGHT4CARB project focuses on the emerging field of photoredox catalysis. The team aims to harness the power of inexpensive, widely available visible light to drive complex chemical reactions. By using light as a primary energy source, the project enables the sustainable and mild synthesis of essential biomolecules, such as non-natural sugars, while drastically reducing chemical waste and energy consumption. These synthetic sugars are critical “building blocks” for a wide range of pharmaceuticals. LIGHT4CARB will hence accelerate the drug discovery pipeline, ensuring that the next generation of high-value medicines is developed through greener, more efficient chemical processes.

“I am delighted that Research Ireland has recognised LIGHT4CARB as a bold blueprint for advancing sustainable photoredox chemistry to access valuable sugar building blocks,” says Dr. Loh. “This award underscores Research Ireland’s commitment to high-quality fundamental research and positions UCD as a leading hub for transformative visible-light-driven synthesis. I am immensely excited to embark on this new research chapter, pushing the frontiers of what is possible using modern light-driven organic synthesis, and to nurture younger generations of chemists with state-of-the-art synthetic strategies.”

GlycoMetalGuard: Led by Dr. Joseph Byrne, GlycoMetalGuard is developing innovative antimicrobial coatings and therapies to prevent hospital-acquired infections stemming from medical devices. Dr. Byrne’s team aims to target harmful bacteria with novel sugar-based metal compounds, supporting efforts to addressing antimicrobial resistance and improving patient safety and quality of life. Combining expertise in inorganic chemistry, carbohydrate chemistry and polymer chemistry within the team and through strategic collaborations puts UCD in a strong position to lead this innovative approach.

Dr. Byrne says, “Prevention of bacterial infections is key to fighting the challenge of antimicrobial resistance. For many vulnerable or immunocompromised patients, medical devices like catheters or endotracheal tubes are essential, but they can also be a risk for infection in hospital. I’m delighted to have the support from Taighde Éireann to build new chemical tools that we hope will enhance medical devices to better protect vulnerable people in Ireland and beyond. Fundamental scientific research is at the foundation of addressing major societal challenges like antimicrobial resistance – my team’s exploration of infection-prevention and new treatments will also train several highly skilled chemistry researchers who will go on to make further contributions to our skills economy.”

For further details, see the announcements at various sources below:

UCD Chemistry | UCD News | UCD Research | Research Ireland | Silicon Republic | UCD Conway Institute

Joe Uncategorized

Lab Awarded Sustainability Certificate

The Byrne Group were delighted to be awarded a Green Certification from MyGreenLabs, as part of Research Ireland’s Sustainable Laboratory Certification Pilot Programme. In Lab A2.01, we worked together with Tom Hooper’s and Andrew Phillips’ Groups to identify sources of waste, establish new recycling streams (e.g. for KimTech gloves), and pool resources where possible to limit duplication of purchases. It was a really worthwhile process and has made us more considerate of reducing negative environmental impacts of our research. Sophie Kavanagh joined a UCD-wide working group on wet lab practices as part of our actions, and we have participated in chemical swap days, further reducing wastage. We continue to meet and share ideas, which will hopefully keep us up to date with developments in this area

Marking the announcement of 72 Sustainable Laboratory Certifications awarded today to research spaces in 12 higher education institutions across Ireland were (left-right) Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD; Prof. Emmanuelle Graciet, Faculty of Science & Engineering, Maynooth University; and Dr Ciarán Seoighe, Deputy CEO, Research Ireland.

Announcing the awards, Minister Lawless said:

“Research involves more than exploration and discovery; it also demands attention to how we conduct our work and the impact it has on our communities and our planet. Research carries with it a responsibility to operate with integrity, to use resources wisely, and to ensure our pursuit of knowledge does not come at an unsustainable cost to the world around us. I warmly congratulate all the laboratory teams recognised today for their commitment to greener practices. This initiative, led by Research Ireland, marks a significant and encouraging step in placing sustainability at the centre of our national research system and signals Ireland’s intent to lead by example on climate-conscious innovation.”

UCD Press Release: 13 UCD labs awarded sustainable laboratory certifications for best-in-class practices

Research Ireland Press Release: Minister Lawless announces 72 Sustainable Laboratory Certifications (with full list of awardees)

Joe Awards, news

Joe and Adele selected to attend Lindau Nobel Laureates Meeting

Joe and our colleague Adele Gabba, both from NUI Galway’s School of Chemistry, have been selected to attend the prestigious meeting of Nobel Laureates and emerging scientists from around the world in 2021. The pair will represent Ireland at the 70th Lindau Nobel Laureate Meeting on the island of Lindau in Germany.

From the NUI Galway press release: Dr Byrne and Dr Gabba will join a selected group of 660 outstanding early-career scientists from 101 countries, who will meet with 68 Nobel Prize winners in the fields of chemistry, medicine and physiology, and physics. Selection to attend this week-long meeting offers a once-in-a-career opportunity to share their research and ideas with Nobel laureates and a wide network of future scientific leaders.

Dr Joseph Byrne is an Honorary Research Lecturer in the School of Chemistry, who is in the first year of a Science Foundation Ireland Starting Investigator Research Grant project, developing luminescent glycoconjugate materials for detection of bacterial infections.

Dr Adele Gabba recently graduated with a PhD in Chemistry and currently works as a research assistant in the group of Professor Paul Murphy, School of Chemistry at NUI Galway. She will begin a prestigious Marie Sklodowska-Curie Individual Fellowship in MIT in the coming months.

Dr Gabba and Dr Byrne were among six scientists nominated by the Irish Research Council (IRC), before going through a rigorous international selection process, through which only half of nominees were ultimately invited to attend. They will receive a grant from the Irish Research Council to enable them to attend the meeting, which takes place from 27 June-2 July 2021. The meeting was scheduled for this summer, but due to the outbreak of COVID-19, it has been postponed until 2021, while an interactive online programme of events will take place this year to fulfil the Lindau Foundation’s mission ‘Educate. Inspire. Connect.’

Joe said:

“This meeting is unique in putting the most ground-breaking scientists of recent decades and early-career researchers around the same tables for a week. With little-to-no distraction from the outside world, it is ideal for transferring ideas and sharing challenges between generations and countries as well as different disciplines. I am looking forward to building new relationships with other chemists, but also biochemists, physicists, medical scientists, who I could collaborate with to tackle challenging scientific questions of international relevance in the future.”

Adele said:

Dr Gabba said: “Being selected to attend a Nobel Laureate Meeting is a small life dream come true! I have been certainly looking forward with immense excitement for June, so I have to confess the news of the postponement for COVID-19 came along with a bit of disappointment. Despite my childlike eagerness, I think the organising committee took the right decision. I am sure all attendees will see that waiting and, most of all, the reason behind it, as an opportunity to reflect deeply on the importance of bringing together researchers with a different background in an interdisciplinary meeting. Problems that impact our society are mostly extremely complex, we will succeed in solving them only if we put our brains and best efforts together.”